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Journal: BMC Medical Imaging
Article Title: Differentiation of non-hypervascular non-functional pancreatic neuroendocrine neoplasms from solid pseudopapillary neoplasms using dual-layer spectral detector CT
doi: 10.1186/s12880-025-02004-5
Figure Lengend Snippet: Feature selection for LASSO regression following univariate analysis. a1 , b1 : Selection of the tuning parameter (λ) for LASSO regression. The area under the curve (AUC) was plotted against log(λ), and fivefold cross-validation was used to determine the optimal λ value—0.248 in the “a1” model and 0.005 in the “b1” model. a2 , b2 : LASSO coefficient profiles for the selected features, with each colored line representing the coefficient path of a specific feature. A vertical black line is drawn at the selected log(λ) values of − 1.393 and − 5.365, respectively, indicating the points at which non-zero coefficients were retained—one (nICa) from the DLCT parameters in model a2, and three (age, nCTa, nICa) from the candidate parameters in model b2. a1 , a2 : DLCT parameters. b1 , b2 : Three candidate parameters. LASSO: least absolute shrinkage and selection operator; DLCT, dual-layer spectral detector CT; prefix n, normalised; suffix a, arterial phase; IC, iodine concentration
Article Snippet: To differentiate between non-hypervascular NF-pNENs and SPNs, independent relevant clinical-radiological features and quantitative parameters were identified using the Least Absolute Shrinkage and
Techniques: Selection, Biomarker Discovery, Concentration Assay